CYCLOPHOSPHAMIDE HEMORRHAGIC CYSTITIS

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Effect of Lycopene on Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats

Background: Cylophosphamide is used alone or in combination with other drugs for treatment of neoplastic diseases. Hemorrhagic cystitis is a major potential toxicity and dose limiting side effect of cyclophosphamide. The aim of this study was to evaluate the effects of lycopene compared with some antioxidants for the prevention of cyclophosphamide induced hemorrhagic cystitis in rats. Methods: ...

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Effect of Lycopene on Cyclophosphamide- Induced Hemorrhagic Cystitis in Rats

Background: Cylophosphamide is used alone or in combination with other drugs for treatment of neoplastic diseases. Hemorrhagic cystitis is a major potential toxicity and dose limiting side effect of cyclophosphamide. The aim of this study was to evaluate the effects of lycopene compared with some antioxidants for the prevention of cyclophosphamide induced hemorrhagic cystitis in rats. Methods: ...

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Free radicals and non-radical reactive molecules as well as several cytokines (e.g. tumor necrosis factor-α and interleukin family) and transcription factors (e.g. nuclear factor-κB and activator protein-1) are now known to take part in the pathogenesis of cyclophosphamide (CP) and ifosfamide (IF) induced hemorrhagic cystitis (HC). When these molecular factors are taken into account pathogenesi...

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effect of lycopene on cyclophosphamide-induced hemorrhagic cystitis in rats

background: cylophosphamide is used alone or in combination with other drugs for treatment of neoplastic diseases. hemorrhagic cystitis is a major potential toxicity and dose limiting side effect of cyclophosphamide. the aim of this study was to evaluate the effects of lycopene compared with some antioxidants for the prevention of cyclophosphamide induced hemorrhagic cystitis in rats.   methods...

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ژورنال

عنوان ژورنال: The Japanese Journal of Urology

سال: 1974

ISSN: 0021-5287,1884-7110

DOI: 10.5980/jpnjurol1928.65.12_816